Sex hormone

Sex steroids, also known as gonadal steroids, are steroid hormones that interact with vertebrate androgen or estrogen receptors. Their effects are mediated by slow genomic mechanisms through nuclear receptors as well as by fast nongenomic mechanisms through membrane-associated receptors and signaling cascades. The term sex hormone nearly always is synonymous with sex steroid.

Male sex hormone easily triggered

Surging testosterone?Scientists have proved that even the most seemingly innocent chat with a woman can be enough to send male sex hormones soaring.
A team from the University of Chicago paid students to come into their lab under the pretence of testing their saliva chemistry.
While there, the students got to chat to a young female research assistant.
Saliva tests showed the brief interaction was enough to raise testosterone levels by as much as 30%.
The more a man's hormone level shot up, the more attractive he later admitted to finding the research assistant.
And perhaps more tellingly, the research assistant herself was able to identify those men who found her attractive.
The men who she judged to be doing the most to try to impress her proved to be those who registered the biggest jump in testosterone levels.
However, little or no change was detected in the saliva of students who chatted with other men.
Animal reaction
Testosterone has long been closely linked with the male libido.
The researchers say their work is the first time that hard evidence has been produced in this way.
It is known that the release of testosterone in animals can embolden them, triggering courtship or aggressive behaviour.
The Chicago team believe the same may be true in humans.
However, lead researcher Dr James Roney said it was also possible that the release of the hormone was stimulated by a stress reaction.
Dr Roney told BBC News Online: "The findings are consistent with the existence of brain mechanisms that are specialised for the regulation of courtship behaviour and thus respond to cues from potential mates with coordinated behavioural and hormonal reactions.
"One might call these reactions components of a "mating response" which, if confirmed by future research, could be as basic and significant as, say, the well-known "fight or flight" reaction."
Dr Nick Neave, of the Human Cognitive Neuroscience Unit at Northumbria University, said the study was "very interesting".
"Other researchers have found changes in male hormone levels after watching erotic movies but this seems to be the first that has attempted to assess hormone changes when males meet women on a more 'normal' level."
Dr Benjamin Campbell, an expert in anthropology at Boston University, said it was possible that testosterone made men more bold by suppressing activity in an area of the brain called the amygdala, which controls the stress reaction.
Testosterone levels peak in a man by his early twenties, and then gradually diminish.
Men who are married or in long-term relationships have lower testosterone levels than those still playing the field.
The research is published in the journal Evolution and Human Behavior.

Estrogen and Testosterone Hormones

The differences between female hormones and male hormones may not be as specific as you might think. The definition of a hormone is a chemical substance produced by an endocrine gland that has a specific effect on the activities of other organs in the body. The major female and male hormones can be classified as estrogens or androgens. Both classes of male and female hormones are present in both males and females alike, but in vastly different amounts. Most men produce 6-8 mg of the male hormone testosterone (an androgen) per day, compared to most women who produce 0.5 mg daily. Female hormones, estrogens, are also present in both sexes, but in larger amounts for women.
Estrogens are the sex hormones produced primarily by a female's ovaries that stimulate the growth of a girl's sex organs, as well as her breasts and pubic hair, known as secondary sex characteristics. Estrogens also regulate the functioning of the menstrual cycle.
In the majority of women, ovarian hormones appear not to play a significant role in their sex drive. In one study of women under the age of 40, 90 percent reported experiencing no change in sexual desire or functioning after sex hormone production was shut down because of the removal of both ovaries.
The Importance of EstrogenEstrogens are important in maintaining the condition of the vaginal lining and its elasticity, and in producing vaginal lubrication. They also help preserve the texture and function of a woman's breasts.
In men, estrogens have no known function. An unusually high level, however, may reduce sexual appetite, cause erectile difficulties, produce some breast enlargement, and result in the loss of body hair in some men.
Androgens are sex hormones produced primarily by a male's testes, but are also produced in small amounts by the female's ovaries and the adrenal gland, an organ found in both sexes. Androgens help trigger the development of the testes and penis in the male fetus. They jump start the process of puberty and influence the development of facial, body and pubic hair, deepening of the voice, and muscle development, the male secondary sex characteristics.
After puberty, androgens, specifically testosterone, play a role in the regulation of the sex drive. Large deficiencies of testosterone may cause a drop in sexual desire, and excessive testosterone may heighten sexual interest in both sexes. However, testosterone levels are poorly correlated with sexual interest and drive when they are within the average range. Sex drive is much more likely to be affected by external stimuli (sights, sound, touch) than by variations in sex hormones, except in extreme cases.
Too Little Testosterone in MenIn men, too little testosterone may cause difficulty obtaining or maintaining erections, but it is not clear whether testosterone deficiencies interfere with female sexual functioning apart from reducing desire.
However, there is no evidence whatsoever to suggest that because women have less testosterone than men do, they have lower sexual interest than their male counterparts. Instead, it seems that women detect and react to much smaller amounts of testosterone in their circulation than men do.

Aging, illness and certain cancer treatments can affect our bodies' delicate hormonal balance, causing changes in sexual interest and functioning. Familiar to most are the changes that occur when a woman goes through menopause. Estrogen production drops throughout this process as a woman exits her child-bearing years.
The major sexual impact of decreased estrogen is a shrinking of the vagina and thinning of the vaginal walls, along with a loss of elasticity and decreased vaginal lubrication during sexual arousal. Some women experience only slight changes in sexual functioning, while others have dryness and pain with intercourse, or genital soreness for a few days after sexual activity, if they don't use a vaginal lubricant or take some form of hormone replacement.
Researchers investigating the effects of hormone replacement therapy on women's sexual functioning have shown that taking estrogen often allows sexual functioning to return to normal. In addition, androgens have been prescribed for postmenopausal women to enhance their sexual desire.
Hormone-Replacement TherapyPerhaps less well known is the fact that men sometimes experience lowered testosterone levels, which can be responsible for sexual dysfunction. How this hormonal decrease affects the man's sex drive and erections remains unclear. But urologists, as a treatment for these difficulties, sometimes recommend testosterone replacement. There is a great deal yet to be learned about which men and women may require and benefit from hormone-replacement therapy.
It is tempting to try to understand sexual behavior solely in terms of hormones. In many animal species hormones that control the female's willingness to mate and the courtship and sexual behavior of the male tightly regulate patterns of sexual behavior.
In humans, however, there is a more complicated relationship between hormones and sexual behavior. Although a substantial testosterone deficiency usually reduces sexual interest in men and women, there are cases in which that effect is not seen.
Similarly, although many men with below normal testosterone levels have difficulty with erections, not all do. Women who have low amounts of estrogen in their bodies do not lose their ability to be sexually aroused or to have orgasms.
In short, sex hormones are not the only factors affecting sexual interest or behavior. If you are concerned about your hormone levels and whether they may be effecting your general health or your sexual functioning, consult your doctor for some easily performed and (almost) painless laboratory blood work.

Lust and Love - Is it more than chemistry?-Royal Society of Chemistry

The Royal Society of Chemistry has come up with ten things you never knew about lust and love, taken from its recently published Lust and Love - Is it more than chemistry? book by Gabriele and Rolf Frobose.

1. The cuddle hormone

Oxytocin - the "cuddle" hormone - is why women like to cuddle up after sex. Their oxytocin levels are much higher after sexual encounters, creating a feeling of closeness and comfort. Men also have oxytocin, but it is compensated for by higher levels of testosterone - so they are less prone to cuddling!

2. 3kg of lipstick in a lifetime!

Miss average will put on around 3kg of lipstick on her lips throughout her lifetime. 92 per cent of women in industrialised countries use lipstick, and it is at the top of the league of items most frequently shoplifted.

3. The sweat effect

The smell of a man's sweat may not be the turn off one might think - an experiment at Northumbria University in 2000 asked 16 students to judge the looks of various men in pictures. Then without the girls' knowledge, a cloth soaked in male sweat was placed in the room and the experiment repeated - with phenomenal results. Men previously judged unattractive were seen in a new light. Even those judged the least attractive in the first viewing were able to catch up to their more handsome rivals in the second viewing. So men could try wiping their sweat on their handkerchief and leaving it showing when they ask out a potential date!

4. The love hormone

Dopamine is a hormone which people in love have generally much higher levels of than those who are unattached. Not enough dopamine can lead to Parkinson's disease or Schizophrenia, while too much can make one a little too amorous - is this why Casanova became pathologically addicted to love?

5. Men and women fancying each other

Is there such a thing as love at first sight? If a woman fancies a man, she will look to make eye contact early in the conversation - even if she is shy! If a man fancies a woman, he will quickly begin asking her questions about herself - but if he doesn't, he will make bland general observations about the weather or other generic topics!


Lust and Love - is it more than just chemistry?


6. The direct approach - men like it, women don't!

American psychologist David Buss carried out a survey on the pulling tactics used by the sexes and found - unsurprisingly - that men are turned on by women wearing tight fitting, revealing clothes; that dance provocatively and have long legs and swinging hips. Most men would also be receptive to a woman "grinding" herself up against him at a bar. Women were much less impressed by corresponding approaches by men - with the study concluding men like explicit behaviour in women, whereas women find it objectionable and sometimes repulsive in men.

7. Sex cures your headache!

Whenever we have sex, we release morphine-like substances called endorphins into our bodies. These hormones - from a group called opiates - are both pleasure causing and natural painkillers - thus sex can cure your headache! Couples who are close are full of these opiates, as are a mother and her new born baby. It is this shared "high" that contributes to the formation of the mother-baby bond.

8. Perfume - chemistry made it cheaper!Many of the natural fragrants used in perfumes are incredibly expensive, so have been replaced by cheaper synthetic alternatives. Although many people would no doubt prefer the real thing, the cost of preparing - for example - one kilogram of attar of roses requires five tonnes of petals, costing some £3,500! Thus synthetic chemistry has made perfumes affordable to the masses.

9. Oysters - aphrodisiac or myth?

Oysters are believed to aphrodisiacs the world over - China and Japan attribute miraculous effects to the Asian Oyster Crassostrea gigas. The Danes go even further - their traditional name for the Oyster is kudefisk, which literally means vulva fish!
However, the Oyster does not have much to offer by way of active ingredients, and it is more likely its semi-liquidity, its somewhat evocative appearance and the taste of salt and sea that are responsible for any love inducing effects! The suggestion of luxury associated with a dinner of oysters by candlelight could also reinforce this "placebo" effect.

10. Eyes not nose to find a mate

Throughout evolution, our ancestors have gradually trust their eyes more than their noses - researchers believe that we are not very good at responding to chemical signals in mating. Some of our primate cousins are much better however - while we always look at each other before mating - the squirrel monkey, much more adept with its nose - will sniff at a potential mate.